More people in the US and Canada are planning a pregnancy while taking, or shortly after stopping, a GLP-1 medication such as semaglutide (Ozempic, Wegovy) or tirzepatide (Mounjaro, Zepbound). The questions we hear most: When should I stop? Do I need different supplements? Should my partner do anything? Here’s a practical, buyer-focused guide — written to help you prepare questions for your prescriber, not to replace them.
This is educational, not medical advice. Decisions about stopping or continuing any prescription belong with your doctor. For the bigger picture, see our guide to fertility supplements to get pregnant.
1. First conversation: your prescriber, not a supplement
GLP-1 medications are not recommended during pregnancy, and the prescribing information for some of them advises stopping ahead of a planned pregnancy — semaglutide labeling, for example, mentions at least 2 months because the medication stays in the body for a while. Tirzepatide labeling also notes it may reduce the effectiveness of oral birth control around the start of treatment and dose increases. Ask your doctor for a written plan: when to stop, what to expect with appetite and weight afterward, and when it’s reasonable to start trying.
2. Why nutrition gaps matter more after a GLP-1
Lower appetite often means eating less overall — and sometimes less protein, iron-rich food, and variety. That’s exactly the window when preconception nutrition matters. A prenatal with folic acid (or folate) is the baseline recommendation for anyone trying to conceive, ideally started before you begin trying. Ask your doctor whether labs such as iron, vitamin D or B12 make sense for you. See our preconception checklist.
3. Where a TTC formula fits — and where it doesn’t
A fertility supplement doesn’t replace the prenatal or medical guidance; it’s an optional layer designed to support reproductive wellness. If you choose one, pick one formula matched to your situation rather than stacking several:
| Your situation | Often considered | Check first |
|---|---|---|
| General TTC support after stopping a GLP-1 | AGO Mom + prenatal | Overlap with your prenatal label |
| Irregular cycles or PCOS history | AGO Eva or AGO Mom | Cycle tracking + doctor review |
| Partner also preparing | AGO Dad for him | Semen analysis if trying 6–12 months |
Before you buy, run your labels through our TTC stack guide to avoid doubling up.
4. Don’t forget him
Weight and metabolic health affect both partners. If he’s also on a GLP-1 or recently lost weight, he should ask his own prescriber about timing. Sperm take roughly 72–90 days to develop, so a men’s formula such as AGO Dad is planned over a full cycle. Couples can compare options in our fertility supplements for couples guide.
5. A simple 90-day plan to bring to your appointment
- Weeks 0–2: Ask your prescriber when to stop and how to handle contraception in the meantime.
- Weeks 2–4: Start a prenatal; review labs if your doctor recommends them; focus on protein and regular meals.
- Weeks 4–12: If you add a TTC formula, take it consistently and track cycles. See how to take fertility supplements.
- Day 90: Review with your doctor. If you’ve been trying 12 months (6 months if 35+), see a fertility specialist.
Results vary and no supplement guarantees pregnancy. Want help mapping this to your timeline? Get a free personalized plan.
FAQ
Can I take fertility supplements while on Ozempic or Wegovy?
Ask your prescriber first. Many people use this window to start a prenatal; whether to add a TTC formula such as AGO Mom depends on your situation and your doctor’s plan.
How long before trying to conceive should I stop a GLP-1?
Follow your doctor and the medication’s labeling. Semaglutide labeling mentions stopping at least 2 months before a planned pregnancy; other GLP-1s may differ.
Do I need a different supplement after a GLP-1?
Not necessarily. The basics are the same: a prenatal with folic acid, good nutrition, and, if you choose, one TTC formula matched to your situation without overlapping nutrients.
Should my partner take a fertility supplement too?
His health matters as much as yours. A men’s formula like AGO Dad is designed to support sperm health over about 90 days; a semen analysis can guide the decision.
Will a fertility supplement help with weight regain after stopping?
No. AGO supplements are designed to support reproductive wellness, not weight management. Ask your doctor about a plan for appetite and weight after stopping.
Do you ship to the US and Canada?
Yes. AGO ships to the US and Canada; the care team can confirm delivery times for your area.